Bee is a macOS app built using native technologies. It is a native interface to GitHub Issues, JIRA and Manuscript.

It's for software professionals who use issue trackers to organise their work and figure out what to do next. It's beautiful and meticulously designed. For that reason alone, it stands out amongst all of the other web-based issue trackers. You shouldn't have to fight your issue tracker, you should be able to use it easily just like any other To Do app.